SAS Server for Analysis of DNA and Protein Sequences

The SAS server at Iowa State University provides the following services:

Identifying genes in a genomic DNA sequence by comparing the sequence against cDNA and protein sequence databases.

Computing pairwise alignments for two DNA sequences, for two protein sequences, for a DNA sequence and a protein sequence, and for a DNA sequence and a cDNA sequence.

Computing a multiple alignment for DNA sequences and for protein sequences.

We would like to thank Volker Brendel and his group for making the server available at ISU. Most of the programs used in the server were developed in the lab of Xiaoqiu Huang in the Department of Computer Science at Iowa State University. The RepeatMasker program was developed by A. Smit and P. Green. The exon sequence statistics used by GSA2 were from the MZEF program developed by Michael Zhang.

The SAS web server was developed by Yan Zhou and improved by Lijie Tu under the supervision of Xiaoqiu Huang. We thank Alessandro Guffanti for allowing us to use and modify his code for the DPS Server. Sequence Assembly with CAP3 program and Finding CpG Islands were added by Liang Ye.