287520     .    :    .    :    .    :    .    :    .    :    .    :
 158478 GCTTTGGGGCTGCA        GGGAAGCTGGCCGCTGT    GGGCGGTCTCGGGCCAG
        ----------||||--------|||||  ||||||  ||----|||||| ||| ||||||
 159038           TGCAGTCCTCTGGGGAATTTGGCCGTGGTGGGCGGGCGGACTCTGGCCAG

 287580     .    :    .    :    .    :    .    :    .    :    .    :
 158526 CCCCGCCCCACCTGTCCTTTTCCTGGAGACTATTAGTCCA GGGTTTGTCCCTGCAGTGC
        ||||||||||||-|| ||| ||   |||||   || ||||-||| ||| ||    ||| |
 159088 CCCCGCCCCACC GTTCTTCTCTCAGAGACCTGTAATCCAGGGGCTTGGCCTCAGAGTCC

 287640     .    :    .    :    .    :    .    :    .    :    .    :
 158585 CATTGGCCTGGCAGGCAGGATCGAGGAGGAAGTGGC                        
        ||||||  || ||||| |||| ||||||||||||||++++++++++++++++++++++++
 159147 CATTGGTTTGACAGGCTGGATAGAGGAGGAAGTGGCCAAGAAACGAAATATATTCTTCCT

              ~~~ 720 bp removed ~~~

 288420     .    :    .    :    .    :    .    :    .    :    .    :
 158981 TCTCCATTGCATTTCTACTTCCAGCCTCTGGGCTCCTGCTTCTGCCTCCTGCTTAGGACC
        ++++++++++++++++++++++++++++++++|||||||||||||||| ||  ||||| |
 159567                                 CTCCTGCTTCTGCCTCTTGTCTAGGATC

 288480     .    :    .    :    .    :    .    :    .    :    .    :
 159041 TGT   CCCCCTGGGTAGCTCACAACACCTCAAACATAGCAGTCAGAGGCCAC       
        | |---|||| || ||||||| || ||||||| |||| |||||| |||| |||+++++++
 159595 TCTTTCCCCCTTGTGTAGCTCGCATCACCTCAGACATGGCAGTCTGAGGGCACATTTGAG

              ~~~ 8940 bp removed ~~~

 297480     .    :    .    :    .    :    .    :    .    :    .    :
 163154 CCTTACTGCATGTGTTGTCACATATGTGCAATGCCATGCTCCTGAGCCTTTGATTGCAGA
        +++++++++++++++++++++++++++++++|||| ||| |||| ||||||| | |||||
 164532                                TGCCTTGCCCCTGTGCCTTTGTTGGCAGA

 297540     .    :    .    :    .    :    .    :    .    :    .    :
 163214 CGTGTGGGAAGTGGGCCCCGTCCCCACCCCCAGTGCCACCCTGCTCTGCTTCTCTTCCCT
        |-||||||||||||||||  -||||||||----||||||||| | --||| |||||||||
 164561 C TGTGGGAAGTGGGCCCTC CCCCACCC    TGCCACCCTCCA  GCTCCTCTTCCCT

 297600     .    :    .    :    .    :    .    :    .    :    .    :
 163274 TGCTGTGCTCTAAAACGAGAAGTACAAGTGAGTTCCCCCAAGGGGTCGGCCGCGCCTCTT
         ||| ||-----||| ||||||| | |||||||||||| ||||||||||||||||| |||
 164613 CGCTCTG     AAAAGAGAAGTTCTAGTGAGTTCCCCTAAGGGGTCGGCCGCGCCCCTT

 297660     .    :    .    :    .    :    .    :    .    :    .    :
 163334 CCTGTCCCCGCCCTGCCGGCTGCCCCAGGCCAGTGGAGTGGCAGCCC             
        |||||| ||||||||| ||||||||||||||||| |||||| |||||+++++++++++++
 164668 CCTGTCTCCGCCCTGCTGGCTGCCCCAGGCCAGTAGAGTGGTAGCCCGGGGAGCAGGACT


Fig. 4.  A portion of a 410,305-bp general alignment of
syntenic human and mouse sequences.
The positions of leftmost bases on each line are given in the left margin.
Difference blocks are indicated by '+' and gaps are indicated by '-'.